chondrogenesis相关论文
气管外伤、狭窄、肿瘤以及部分先天性疾病可严重损伤正常通气功能,引起组织缺氧,危及患者的生命。气管病变切除重建是治疗这些疾病最......
MicroRNA-92a-3p regulates the expression of cartilage-specific genes via directedly targeting histon
Objective:Increased activity of histone deacetylase 2(HDAC2)has been described in patients with osteoarthritis(OA)andcar......
Loss of ERK1and ERK2in progenitor cells causes metachondromatosis by enhancing chondrogenesis in viv
Metachondromatosis(MC)is a rare hereditary disorder involving the formation of enchondromas and osteochondromas.Recently......
Objective:ToinvestigatethespecificroleofZeb1inlimbmesenchymeduringskeletaldevelopment....
Isolation and characterization of Meniscus derived stem cells from rabbit as a possible treatment fo
Background The successful surgical restoration of damaged meniscus has been a challenge,largely owing to a lack of chara......
How distration arthroplasty works:chondrogenesis of cartilage progenitor cells under the stimulation
Objective:The purpose of this study was to explore the effects of intermittent hydrostatic pressure(IHP)on chondrogenicd......
INTRODUCTION Chondrogenesis is a common sign of tendinopathy,especially in athletes,but the mechanism of chondrogenesis ......
Opposite Regulation of Chondrogenesis and Angiogenesis in Cartilage Repair ECM Materials under Hypox
Backgroud: Though cartilage tissue engineering has been developed for decades,it is still unclear whether angiogenesis w......
Mesenchymal stem cells(MSCs)are considered to be a suitable cell type for tissue regeneration.However,to different sub-p......
Regulationofglucoseconcentrationinexpansionperiodonthesynovialmensenchymalstemcellschon
Background: TotestandverifythehypothesisthatglucoselevelsregulatestheproteinkinaseCactivityand transforminggrowthfactor-......
DirectingChondrogenicDifferentiationofMesenchymalStemCellswithaMatrix-SupportedChitosanHy
Purpose: Hydrogelsareattractiveforcartilagetissueengineeringbecauseoftheirhighplasticityandsimilaritywiththenativecartil......
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Effect of Link N on the expression of chondrogenic and osteogenic genes in human bone marrow-derived
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Melatonin retrieves pro-inflammatory cytokine-inhibited chondrogenesis in human synovium-derived ste
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Hypoxia Promotes Chondrogenic Differentiation in Growth Differentiation Factor 5-Induced Human Mesen
It is widely known that hypoxia can promote chondrogenesis of human Bone Marrow-Derived Mesenchymal Stem Cells (hMSCs) i......
Cell-bricks Based in Jectable Niche Guided Persistent Ectopic Chondrogenesis of BMSCs and Enabled Na
Purpose: Developing cartilage construct with injectability,appropriate matrix composition and persistent cartilaginous p......
XBP1S,a BMP2-inducible transcription factor,Accelerates Endochondral Bone Growth by activating GEP G
We reported earlier that transcription factor XBP1S binds to RUNX2 and enhances chondrocyte hypertrophy through function......
Hypoxia enhances engineered chondrogenesis through modulating glucose metabolism mediated by HIF-1al
Articular cartilage,a highly organized avascular connective tissue with substantial durability,has very limited capacity......
Reconstruction of Extracellular Matrix Microenvironment to Facilitate Expansion and Chondrogenesis o
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Introduction BMP2 is known to activate ER stress signaling molecules, including XBP1S and ATF6.We previously reporte......
Chondrogenesis of Human Adipose-Derived Stem Cells by In Vivo Co-graft with Auricular Chondrocytes f
Objective: To evaluate the efficiency of chondrogenesis of human adipose-derived stem cells (ADSCs) induced by auric......
CCN家族属于基质细胞蛋白,富含半胱氨酸蛋白61(CYR61)是其中第一个被克隆的基因.CYR61蛋白参与调节细胞的增生、黏附、迁移、分化......
Construction of Self-Assembled Cartilage Tissue from Bone Marrow Mesenchymal Stem Cells Induced by H
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Induction of Chondrogenesis of Adipose-derived Stem Cells by Novel Recombinant TGF-β3 Fusion Protein
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软骨组织的研究一直依赖于哺乳动物胚胎模型,这种方法存在取材困难、难以明确界定分层边界等弊端.而鹿茸非常独特,可以作为一种新......
,Resveratrol protects bone marrow mesenchymal stem cell derived chondrocytes cultured on chitosan-ge
Aim: To investigate the effects of resveratrol on interleukin-lbeta (IL-1β) induced catabolism in bone marrow mesenchym......
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,Enamel Matrix Derivative Stimulates Osteogenesis-and Chondrogenesis-related Transcription Factors i
Our purpose was to determine how enamel matrix derivative (EMD) affects the expression of osteogenesis-and chondrogenesi......
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目的 检测组蛋白去乙酰化酶7(HDAC7)是否为MicroRNA(miRNA)-140的靶基因,并研究在大鼠骨髓间充质干细胞(ratMSCs)成软骨诱导分化中......
目的:观察延迟性周期性动态压缩应力对立体培养条件下骨髓间充质干细胞成软骨分化的影响,探讨力学因素在软骨分化过程中的作用机制。......
Background Synovium-derived stem cells (SDSCs) with higher chondrogenic potential are attracting considerable attention ......
胚胎干细胞因其具有体外无限增殖能力和体内外分化发育的全能性,有望为细胞治疗或组织工程化组织构建提供可靠的种子细胞来源.如何......
目的 评价人类脂肪来源成体干细胞(hADASc)体外培养转基因定向成软骨诱导的可行性.方法 hADASc体外培养后行PGL3.转化生长因子β1(......
利用阿利新蓝、甲苯胺蓝、茜素红染色和免疫组化法鉴定鹿茸间充质干细胞(MSCs)不同分化阶段蛋白多糖、Ca2+和Ⅱ型胶原蛋白3种软骨细......
Chondrogenesis of periodontal ligament stem cells by transforming growth factor-b3 and bone morphoge
The periodontal ligament-derived mesenchymal stem cell is regarded as a source of adult stem cells due to its multipoten......
目的:研究人骨髓问充质干细胞(mesenchymal stem cells,MSCs)在体外培养过程中的增殖和成软骨分化现象和规律。方法:以密度梯度离心法分......
长链非编码RNA(lncRNA)是生物发育过程中重要的调控因子。同属非编码RNA的miRNA已经证实在软骨细胞再生和骨关节炎发病机制中发挥......
目的软骨微环境对软骨形成具有重要作用。本实验探讨软骨细胞与成纤维细胞共培养体外构建软骨的可行性。方法分别培养猪软骨细胞与......
Systematic review on the use of autologous matrix-induced chondrogenesis for the repair of articular
AIM To systematically review the results of studies looking at autologous matrix-induced chondrogenesis(AMIC)in humans.M......
低氧对多种组织的正常生长发育至关重要,低氧诱导因子1(HIF-1)是多细胞生物在低氧条件下维持自身氧稳态的关键因子,可促进血管生成......
目的:探讨多聚左旋赖氨酸(PL)对大鼠肢芽细胞向软骨细胞分化的促进作用及其可能机制。方法:取大鼠肢芽细胞在含不同剂量PL的培养液中培......
FGFR3是成纤维细胞生长因子受体(fibroblastgrowthfactorreceptors,FGFRs)家族成员之一,在骨骼发育中起重要作用。FGFR3的激活突变......
目的探讨人骨髓间充质干细胞(mesenchymal stem cells, MSCs)向软骨细胞诱导分化的能力.方法选用不同代次的MSCs,使用条件培养基,......
Y染色体性别决定区(sex-determing region of Y chromosome,SRY)-盒转录因子9(SRY-box transcription factor 9,Sox9)在软骨细胞分......
Accelerated chondrogenesis in nanofiber polymeric scaffolds embedded with BMP-2 genetically engineer
This study evaluated chondrogenesis within a nanofiber polymeric scaffold seeded with isolated untreated chondrocytes, i......
Osteoarthritis is a debilitating disease that affects hundreds of millions of people worldwide. Current research involvi......
The limited intrinsic healing potential of human articular cartilage is a well-known problem in orthopedic surgery.Thus ......
In the well-known superfamily of transforming growth factors beta (TGF-b), bone morphogenetic proteins (BMPs) are one of......